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What Is The Advantage of Electrospun Cellulose Acetate (CA) Nanofibers?

2020-07-02



Scanning electron microscopy images of (A) as-spun CA fiber mat from 17% (w/v) CA dissolved in a mixture of acetone/DMAc (2:1, v/v) containing 5 wt% vitamin E, (B) as-cast CA film from 4% (w/v) CA dissolved in a mixture of acetone/DMAc (2:1, v/v) containing 5 wt% vitamin E, (C and D) vitamin Eeloaded as-spun CA fiber mats after immersion in (C) B/T or (D) B/T/M medium for 24 h, as-spun CA fiber mat fabricated from (E) 17% (w/v) and (F) 4% (w/v) of CA dissolved in a mixture of acetone/DMAc (2:1, v/v) containing 0.5 wt% retin-A, and retin-A-loaded as-spun CA fiber mats after immersion in (G) B/T or (H) B/T/M medium for 6 h. CA, cellulose acetate; DMAc, dimethylacetamide; B/T stands for the releasing medium prepared by adding 0.5% of a non-ionic surfactant and Tween 80 to the acetate buffer solution; B/T/M stands for the releasing medium prepared by adding 0.5% of Tween 80 and 10% of methanol in the acetate buffer solution

Lipase is an enzyme widely used in the production of dairy products, bakeries, fats, and oils. The modification of polyethylene glycol diacyl chloride on the nanofiber surface provides more reactive sites for the lipase enzyme, and the immobilization process does not affect its activity.

 

Cellulose acetate (CA) nanofibers with immobilization of vitamin A and E have an average diameter of 247-265 nm, with a smooth surface and round cross-section. The morphology of the loaded nanofibers is shown in Figure. Compared with the cast film of CA, the release of vitamins from electrospun nanofibers is sustained.

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